Heinritz H, Benzel W, Hoffmann K, Iro H
Klinik und Poliklinik für Hals-Nasen-Ohrenkranke, Universität Erlangen-Nürnberg.
HNO. 1995 Jan;43(1):6-11.
In order to improve the preoperative diagnosis of superficial skin tumors in the head and neck, 32 patients with 42 basal cell carcinomas, squamous cell carcinomas and malignant melanomas were investigated using different imaging techniques. All patients were examined preoperatively with high-frequency ultrasound (HFU), computed tomography (CT) and magnetic resonance imaging (MRI). New high-frequency ultrasonic scanners (15- and 20-MHz) having an axial resolution of 50-90 microns permit visualization of dermal and cartilaginous structures with an anatomical accuracy to a range of 15 mm in tissue. Exact measurement of the skin tumors and their relation to adjacent structures was feasible. Histologically different tumors could be discriminated by their echo-structure in 80% of the cases. CT and MRI provided additional information when the tumor extension perpendicular to the skin exceeded 15 mm. If tumor extension was less than 15 mm, CT and MRI were inferior to high-frequency ultrasound in the diagnosis of superficial skin tumors and did not provide any additional information. The experience reported has shown that high-frequency ultrasound is a valuable tool for preoperative evaluation of superficial skin tumors in terms of tumor extension and possible invasion of functionally and esthetically important adjacent structures. This knowledge can support preoperative planning of possible resections as well as reconstruction and may help to obtain an appropriate informed consent.
为提高头颈部浅表皮肤肿瘤的术前诊断水平,我们使用不同成像技术对32例患有42处基底细胞癌、鳞状细胞癌和恶性黑色素瘤的患者进行了研究。所有患者术前均接受了高频超声(HFU)、计算机断层扫描(CT)和磁共振成像(MRI)检查。新型高频超声扫描仪(15兆赫和20兆赫)轴向分辨率为50至90微米,能够以解剖学精度清晰显示真皮和软骨结构,深度可达组织内15毫米范围。对皮肤肿瘤及其与相邻结构的关系进行精确测量是可行的。在80%的病例中,通过回声结构可区分组织学上不同的肿瘤。当肿瘤垂直于皮肤的扩展超过15毫米时,CT和MRI能提供更多信息。如果肿瘤扩展小于15毫米,在浅表皮肤肿瘤诊断方面,CT和MRI不如高频超声,且无法提供任何额外信息。报告的经验表明,就肿瘤扩展以及对功能和美观重要的相邻结构可能的侵犯而言,高频超声是术前评估浅表皮肤肿瘤的宝贵工具。这些信息有助于支持可能的手术切除及重建的术前规划,并可能有助于获得适当的知情同意。