Raus I
Fortschr Med. 1976 Oct 7;94(28):1579-82.
In a controlled clinical trial Frubienzym (throat lozenges with 5 mg lysozyme, 2 mg papaine and 200 I.U. bacitracin) or placebo have been given to 100 patients with pharyngitis and/or tonsillitis for 4 days. Under treatment with Frubienzym reddening, swelling, matter and mucus in the throat, coughing, swelling and pain of lymphatic ganglions and pain of swallowing vanished more quickly than under placebo. The differences were significant (p less than 0,05, p less than 0,001 or even p less than 0,001; U-test of Wilcoxon, Man and Whitney). There were no side effects which could be attributed to Frubienzym.
在一项对照临床试验中，100名患有咽炎和/或扁桃体炎的患者接受了4天的弗鲁比酶（含5毫克溶菌酶、2毫克木瓜蛋白酶和200国际单位杆菌肽的喉含片）或安慰剂治疗。使用弗鲁比酶治疗时，咽喉部的发红、肿胀、分泌物和黏液、咳嗽、淋巴结肿大和疼痛以及吞咽疼痛比使用安慰剂时消失得更快。差异具有显著性（p小于0.05、p小于0.001甚至p小于0.001；Wilcoxon、Man和Whitney的U检验）。没有可归因于弗鲁比酶的副作用。
