Zak I T, Seabold J E, Gurll N J
Department of Radiology, University of Iowa College of Medicine, Iowa City 52242.
Clin Nucl Med. 1995 Jan;20(1):31-6. doi: 10.1097/00003072-199501000-00008.
Thallium-201 and, recently, Tc-99m MIBI have been used in conjunction with I-131 scintigraphy for follow-up of patients with well-differentiated thyroid cancer. Insular carcinoma of the thyroid is a fairly aggressive thyroid neoplasm that is believed to arise from follicular cells and usually concentrates I-131. The authors report a patient with recurrent insular thyroid carcinoma in whom bilateral adrenal and lung metastatic lesions developed 3 years after ablative I-131 therapy for cervical lymph node and skeletal metastases. Tc-99m MIBI planar and SPECT images demonstrated these new lesions better than pretherapy I-131 scintigraphy and affords an imaging technique for post-I-131 therapy follow-up that does not require withholding thyroid hormone suppression.
铊 - 201以及最近的锝 - 99m甲氧基异丁基异腈（MIBI）已与碘 - 131闪烁显像联合用于分化型甲状腺癌患者的随访。甲状腺岛状癌是一种侵袭性较强的甲状腺肿瘤，被认为起源于滤泡细胞，通常会摄取碘 - 131。作者报告了一名复发性甲状腺岛状癌患者，该患者在接受碘 - 131消融治疗颈部淋巴结和骨转移3年后出现双侧肾上腺和肺部转移灶。锝 - 99m MIBI平面显像和单光子发射计算机断层扫描（SPECT）图像比治疗前碘 - 131闪烁显像能更好地显示这些新病灶，并提供了一种碘 - 131治疗后随访的成像技术，该技术无需停用甲状腺激素抑制治疗。
