Mazo E B, Koriakin M V, Akopian A S
Khirurgiia (Mosk). 1994 Dec(12):28-33.
Eighty-four patients with left varicocele were subjected to complex examination to identify the causes of disturbed spermatogenesis. It was found that not only the testis but the adrenal also is involved in the pathological process in varicocele caused by venous renal hypertension. Changes of venous hemodynamics in the left adrenal lead to activation of steroidogenesis in its cortex and, consequently, to impairment of spermatogenesis in both testes. As the result of the study a new method for the treatment of sterility in patients with left varicocele was suggested, namely, X-ray-guided endovascular occlusion of the central vein of the left adrenal. Tentative evaluation of the results of the intervention gives hope of its efficacy.
对84例左侧精索静脉曲张患者进行了综合检查，以确定精子发生障碍的原因。研究发现，在由肾静脉高压引起的精索静脉曲张的病理过程中，不仅睾丸，肾上腺也参与其中。左肾上腺静脉血流动力学的改变导致其皮质类固醇生成激活，进而导致双侧睾丸精子发生受损。作为研究结果，提出了一种治疗左侧精索静脉曲张患者不育症的新方法，即X线引导下左肾上腺中央静脉血管内闭塞术。对干预结果的初步评估为其有效性带来了希望。
