Sim F H, Frassica F J, Unni K K
Department of Orthopedics, Mayo Clinic, Rochester, MN 55905.
Orthopedics. 1995 Jan;18(1):19-23. doi: 10.3928/0147-7447-19950101-05.
Of 1000 osteosarcoma cases recorded in the Mayo Clinic records, approximately 7% of the lesions occurred in the diaphysis of long bones, mostly in the femur, tibia, and humerus. The average age of the patients with these lesions was 28 years (range: 8 to 67). The duration of their symptoms before diagnosis was greater than that for patients with conventional osteosarcoma in the metaphysis. In approximately 20% of the cases, the radiographic appearance mimicked that of Ewing's sarcoma. Amputation surgery was the major form of treatment. The 2-, 5- and 15-year survival was 42%, 29%, and 20%, respectively.
在梅奥诊所记录的1000例骨肉瘤病例中，约7%的病变发生在长骨干，主要位于股骨、胫骨和肱骨。这些病变患者的平均年龄为28岁（范围：8至67岁）。他们在诊断前的症状持续时间比干骺端传统骨肉瘤患者更长。在约20%的病例中，影像学表现类似尤因肉瘤。截肢手术是主要的治疗方式。2年、5年和15年生存率分别为42%、29%和20%。
