Maestri A, Santini A, Donati D, Gilli G
Servizio di Oncologia Medica, Azienda ospedaliera, Arcispedale S. Anna, Ferrara.
Recenti Prog Med. 1994 Dec;85(12):576-8.
Primary malignant lymphomas of the breast are extremely rare, accounting for only 0.04% to 0.53% of all breast malignancies. Recently a connection between some primary breast lymphomas and mucosa-associated lymphoid tissue (MALT) has been reported identifying an extranodal lymphoma as MALT-type bears some biologic relevance, especially in terms of its spread to other mucosal sites, which sometimes occurs before disseminating into peripheral lymphoid tissue. The Authors report a case of primary breast lymphoma associated with a possible connective disease. Nevertheless the case reported cannot confirm a precise time relationship between malignant lymphomas and autoimmunity, we think that it can be possible.
原发性乳腺恶性淋巴瘤极为罕见，仅占所有乳腺恶性肿瘤的0.04%至0.53%。最近有报道称，一些原发性乳腺淋巴瘤与黏膜相关淋巴组织（MALT）之间存在关联，确定一种结外淋巴瘤为MALT型具有一定生物学意义，特别是在其扩散至其他黏膜部位方面，这种扩散有时会在扩散至外周淋巴组织之前发生。作者报告了一例与可能的结缔组织病相关的原发性乳腺淋巴瘤病例。然而，所报告的病例无法证实恶性淋巴瘤与自身免疫之间的确切时间关系，我们认为这是有可能的。
