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子宫肉瘤。关于25例病例

[Uterine sarcoma. Apropos of 25 cases].

作者信息

Bennani O, Himmi A, Laghzaoui M, Aderdour M

机构信息

Service de Gynécologie-Obstétrique, CHU Ibn Rochd, Casablanca, Maroc.

出版信息

Rev Fr Gynecol Obstet. 1995 Jan;90(1):12-6.

PMID:7899765
Abstract

This study involved an analysis of 25 cases of sarcoma of the uterine body collected at the Gynecology and Obstetrics Clinic of the Ibn Rochd CHU teaching hospital, Casablanca (Morocco) during a 15-year period (1977-1992). These are unusual malignant tumours (accounting for only 0.9% of uterine cancers) which occur after the menopause and have an appalling prognosis. Metrorrhagia was the most common alerting symptom. Presurgical diagnosis was difficult and uterine sarcoma was usually identified during surgery. The most common histological type encountered was leiomyosarcoma. Treatment was primarily surgical: total hysterectomy combined with bilateral appendectomy (20 cases), with radiotherapy (5 cases) or with adjuvant chemotherapy (1 case). Radiotherapy was the only treatment in 2 patients. The survival rate was low: 10% after 2 years, 5% after 5 years. Age, histological type, extent of the tumor and method of treatment were all recognised as prognostic factors. One interest of this work is to recall the existence and the severity of this pathology in those periods of endoscopic games and excessive conservative treatments.

摘要

本研究对摩洛哥卡萨布兰卡伊本·罗什德大学医院妇产科诊所15年间(1977 - 1992年)收集的25例子宫体肉瘤病例进行了分析。这些是罕见的恶性肿瘤(仅占子宫癌的0.9%),发生于绝经后,预后极差。子宫出血是最常见的警示症状。术前诊断困难,子宫肉瘤通常在手术中才得以确诊。最常见的组织学类型是平滑肌肉瘤。治疗主要为手术治疗:全子宫切除术联合双侧附件切除术(20例),联合放疗(5例)或辅助化疗(1例)。2例患者仅接受了放疗。生存率较低:2年后为10%,5年后为5%。年龄、组织学类型、肿瘤范围和治疗方法均被认为是预后因素。这项工作的一个意义在于,在内镜技术发展和过度保守治疗的时期,唤起人们对这种病理状况的存在及其严重性的认识。

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