多发性骨髓瘤：新加坡国立大学医院（NUH）的经验。
Multiple myeloma: the National University Hospital (NUH) experience.
作者信息
Lim H L, Teo C P, Wong K, Kuperan P, Suri R, Tan Y O, Kueh Y K
机构信息
Department of Medicine, National University Hospital, Singapore.
出版信息
Singapore Med J. 1994 Aug;35(4):371-3.
The aim of this retrospective study was to define the characteristics of local patients with multiple myeloma. Twenty-nine de novo cases were accrued from October 1986 to January 1992 at the National University Hospital of Singapore. Features like median age of presentation, sex distribution, the incidence of IgG, IgA and light chain subtypes were similar to published data. However IgD myeloma appeared to be more common here and it tended to be more advanced at presentation. Objective response rate to treatment with the melphalan-prednisolone combination was about 40% with a median survival of 18 months.
这项回顾性研究的目的是明确新加坡本地多发性骨髓瘤患者的特征。1986年10月至1992年1月期间，新加坡国立大学医院累计收治了29例初发病例。其发病年龄中位数、性别分布、IgG、IgA和轻链亚型的发生率等特征与已发表的数据相似。然而，IgD骨髓瘤在本地似乎更为常见，且发病时往往病情更严重。美法仑-泼尼松联合治疗的客观缓解率约为40%，中位生存期为18个月。
Zotero 插件