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[成人胱氨酸病角膜移植中的性染色质测定(作者译)]

[Sexchromatin determination in a corneal graft in adult cystinosis (author's transl)].

作者信息

Hager H D, Kraus-Mackiw E, Schroeder T M

出版信息

Klin Monbl Augenheilkd. 1976 Aug;169(2):234-9.

PMID:790001
Abstract

On the basis of the distribution of F-bodies (Y-Chromatin) and Barr-bodies (X-Chromatin) in a lamellar keratoplasty from a female donor and in the surrounding male corneal tissue of a 55-year-old male patient with adult cystinosis a few female corneal epithelial cells could be identified 7 years after corneal tissue-graft had been performed. It was concluded that after keratoplasty epithelial cells grow into each other, i.e. from the graft to the host tissue and vice versa. The fact that even after 7 years female epithelial cells from the donor can still be detected is put down to the metabolic condition resulting in cystinosis.

摘要

在一位成年胱氨酸病55岁男性患者接受的板层角膜移植术中,取自女性供体的角膜组织及周围男性角膜组织中,依据F小体(Y染色质)和巴氏小体(X染色质)的分布情况,在角膜组织移植7年后可识别出少量女性角膜上皮细胞。得出的结论是,角膜移植术后上皮细胞相互生长,即从移植物向宿主组织生长,反之亦然。即使7年后仍能检测到来自供体的女性上皮细胞这一事实归因于导致胱氨酸病的代谢状况。

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