Dreval' A V, Batashov M G
Ter Arkh. 1994;66(12):83-6.
Fifty-five patients aged 15-35 years with insulin-dependent diabetes mellitus lasting 3.8 +/- 1.2 years underwent carbohydrate food loading. Within 2 hours after the meal, at 15-min intervals measurements were made of glycemia, C-peptide, insulin, glucagon, hydrocortisone, blood STH levels. Contrary to foodstuffs with low glycemia indices (GI), i.e. vermicelli, buckwheat, the intake of fast absorbed products with high GI (potatoes, hardtack, bread) stimulates glycemia and residual secretion of the islet cells. Enhanced entrance of gastrointestinal glucose into the systemic blood flow and growing insulinemia aroused glucagon secretion depression. The body responses to the above processes, assessed as metabolic stress, with increasing blood hydrocortisone and STH concentrations.
55名年龄在15至35岁之间、胰岛素依赖型糖尿病病程为3.8±1.2年的患者接受了碳水化合物食物负荷试验。餐后2小时内，每隔15分钟测量一次血糖、C肽、胰岛素、胰高血糖素、氢化可的松、血液生长激素水平。与低血糖指数（GI）的食物（如细面条、荞麦）相反，高GI的快速吸收产品（土豆、硬饼干、面包）的摄入会刺激血糖升高和胰岛细胞的残余分泌。胃肠道葡萄糖进入全身血流的增加以及胰岛素血症的增加引起了胰高血糖素分泌的抑制。身体对上述过程的反应，以代谢应激来评估，表现为血液中氢化可的松和生长激素浓度的增加。
