Mazurets A F, Kubyshkin V F, Dziuba M V
Lik Sprava. 1994 Jul-Aug(7-8):109-12.
Using methods of cytochemical investigation of the blood polymorphonuclear leucocytes (PMNL), parameters have been studied, characterizing the systems of biological defence and bioenergetics in patients with dilated cardiomyopathy (DCMP), infectious allergic myocarditis (IAM) and myocarditic cardiosclerosis (MCS). DCMP patients showed depression of NBT--test against the background of the increase in the cationic proteins (CP) level in the blood PMNLs, which was a major cytochemical feature. G-6-PhDG activity was increased in IAM patients against the background of high values of NBT-test. Increased values for G-6-PhDG, CP, phosphatases in the presence of low levels of myeloperoxidase in the blood PMNL suggest chronic inflammatory process in the myocardium. Investigation into the cytochemical parameters of bioenergetic and biological defence of the blood PMNL in patients with DCMP, IAM and MCS permits optimization of the diagnosis and treatment policy in the aforementioned nosological entities.
运用血液多形核白细胞（PMNL）的细胞化学研究方法，对扩张型心肌病（DCMP）、感染性过敏性心肌炎（IAM）和心肌硬化性心肌病（MCS）患者的生物防御和生物能量系统相关参数进行了研究。DCMP患者在血液PMNL中阳离子蛋白（CP）水平升高的背景下，NBT试验呈抑制状态，这是主要的细胞化学特征。在NBT试验值较高的背景下，IAM患者的G-6-PhDG活性增加。血液PMNL中髓过氧化物酶水平较低时，G-6-PhDG、CP、磷酸酶的值升高提示心肌存在慢性炎症过程。对DCMP、IAM和MCS患者血液PMNL的生物能量和生物防御细胞化学参数进行研究，有助于优化上述疾病实体的诊断和治疗策略。
