Gavrish A S, Babov K D, Sergienko O V, Viatchenko E V, Poradun E N
Lik Sprava. 1994 Jul-Aug(7-8):51-6.
Functional state and morphological features of platelets were studied in patients with ischemic heart disease 3-24 months following the primary infarction and reinfarction. The studies made pointed to considerable changes in the structure, metabolism and reactivity of platelets. Chronic exposure to irritant factors makes for the depletion and destabilization of blood plates, their adhesive properties and ability to store and catabolize biogenic amines being upset, the destructive changes of glycocalix having a most pronounced impact on the platelet reactivity. The structural and functional disturbances revealed in the thrombocyte homeostasis have been found to correlate with the clinical course of the illness.
对患有缺血性心脏病的患者在初次梗死和再次梗死3至24个月后血小板的功能状态和形态特征进行了研究。所做的研究表明血小板的结构、代谢和反应性发生了相当大的变化。长期暴露于刺激因素会导致血小板耗竭和不稳定，其黏附特性以及储存和分解生物胺的能力受到破坏，糖萼的破坏性变化对血小板反应性影响最为明显。已发现血小板内环境稳定中出现的结构和功能紊乱与疾病的临床病程相关。
