Lopukhov I G, Andrusenko M P, Vladimirova T V, Platonova T P, Chakhava V O
Zh Nevrol Psikhiatr Im S S Korsakova. 1994;94(5):76-81.
The authors studied therapeutic properties of fluoxetine in the treatment of 100 patients with endogenous depressions. The drug was introduced during 6 weeks in a daily dose 20 mg. On the basis of the analysis of its clinical action and adverse reactions, fluoxetine belonging to the class of antidepressants has been ascertained. A prevalence of thymoleptic and stimulating components in its action, equal by their degree of expressivity and a smaller degree of anxiolytic effect have been demonstrated. Differentiated indications to fluoxetine prescription, its predilection in the therapy of apatho-adynamic and melancholic depressions and the feasibility of its use in inpatient conditions are discussed.
作者研究了氟西汀治疗100例内源性抑郁症患者的治疗特性。该药物在6周内以每日20毫克的剂量给药。基于对其临床作用和不良反应的分析，已确定氟西汀属于抗抑郁药类别。已证明其作用中抗抑郁和刺激成分的普遍性，其表达程度相同，且抗焦虑作用程度较小。讨论了氟西汀处方的差异化适应症、其在治疗无动力性和抑郁性抑郁症中的偏好以及在住院条件下使用的可行性。
