Soeiro Fidalgo de Matos C, Nogaret J M, Philippson C, Veys I, Van Velthoven R
Clinic of Mammo-Pelvic Surgery, Institut Jules Bordet, U.L.B. Brussels, Belgium.
Acta Chir Belg. 1995 Jan-Feb;95(1):38-43.
Between 1988 and 1991, at the Jules Bordet Institute in Brussels, 11 patients were submitted to a surgical treatment due to an uterus cervix central recurrence. The majority were of the epidermoid type. The primary stage of the lesion at the moment of diagnosis varied from stage Ib to stage IIIb lesions. Six of the eleven patients were not submitted to an adequate initial treatment. These recurrences appeared between the 4th and the 264th month after the initial treatment. The treatments, which were determined according to the site of recurrence, consisted of: an anterior pelvic exenteration for four patients, a total exenteration for one patient, for two of them a total hysterectomy with bilateral salpingo-oophorectomy and partial cystectomy, a cervix amputation for another one and finally, for the last three ones, a laparotomy with debulking or derivation colostomy. The mortality during and after the operation was nil but there were several short term complications. After a minimal 19 months follow-up we could see that three patients survived, one was generalized and seven died. Due to the scarce number of patients and pathological disparity of them, the authors reviewed the literature concerning this problem, in order to determine some guidelines for similar cases. In spite of its consequences, surgery seems to be the only valid solution to propose to these patients, not only to give them a chance to survive but also to improve their life quality.
1988年至1991年间，在布鲁塞尔的朱尔斯·博尔德研究所，11名患者因子宫颈中心复发接受了手术治疗。大多数为表皮样类型。诊断时病变的原发阶段从Ib期到IIIb期不等。11名患者中有6名未接受充分的初始治疗。这些复发发生在初始治疗后的第4个月至第264个月之间。根据复发部位确定的治疗方法包括：4名患者行前盆腔脏器清除术，1名患者行全脏器清除术，2名患者行全子宫切除术加双侧输卵管卵巢切除术及部分膀胱切除术，1名患者行宫颈切除术，最后，对于最后3名患者，行剖腹减瘤术或转流结肠造口术。手术期间及术后死亡率为零，但有一些短期并发症。经过至少19个月的随访，我们发现3名患者存活，1名患者全身转移，7名患者死亡。由于患者数量稀少且病理情况各异，作者回顾了有关该问题的文献，以便为类似病例确定一些指导原则。尽管有其后果，但手术似乎是向这些患者提出的唯一有效解决方案，不仅能给他们生存的机会，还能提高他们的生活质量。
