Schneider E, Fischer P A, Jacobi P
Med Klin. 1976 Sep 24;71(39):1611-6.
In 50 patients suffering from local cerebral circulation disturbances the effects of bencyclan--administered intravenously in a dosis of 500 mg per day--were evaluated under double-blind conditions. At the same time all patients received digitalis and physiotherapy. Besides a detailed recording of the neurological and psychopathological status a number of psychological tests were applied in order to get objective data about psychomotor function, cerebro-organic capacity and mood. The control recordings after a three weeks' treatment demonstrated an improvement of the clinical as well as the psychological parameters in either group. There were no marked, statistically significant differences in the extent of improvement between the bencyclan and the placebo group; that means bencyclan has no effect on the signs of ischaemic cerebrovascular disease, which exceeds the effects of digitalis and physiotherapy.
在50例患有局部脑循环障碍的患者中，在双盲条件下评估了每天静脉注射500毫克苄环烷的效果。同时，所有患者均接受了洋地黄治疗和物理治疗。除了详细记录神经和精神病理状态外，还进行了多项心理测试，以获取有关精神运动功能、脑器质性能力和情绪的客观数据。经过三周治疗后的对照记录显示，两组的临床和心理参数均有改善。苄环烷组和安慰剂组在改善程度上没有明显的统计学显著差异；这意味着苄环烷对缺血性脑血管疾病体征没有超出洋地黄和物理治疗效果的影响。
