Mocek F W, Richardson R, Williams R, Richardson J D
Department of Surgery, University of Louisville, KY 40292.
J Ky Med Assoc. 1993 Sep;91(9):403-7.
The Zollinger-Ellison syndrome, which is due to the secretion of gastrin from non-beta islet cell tumors of the pancreas, results in gastric hypersecretion and severe peptic ulcer disease. In the 1970s H2 blockers became the mainstay of therapy. More recent evidence indicates that early surgical intervention aimed at tumor extirpation results in improved outcome. The purpose of this paper is to report the case histories of three patients with Zollinger-Ellison syndrome and to review the current literature on management of patients with this syndrome.
卓-艾综合征是由于胰腺非β胰岛细胞瘤分泌胃泌素所致，可导致胃酸分泌过多和严重的消化性溃疡病。20世纪70年代，H2受体阻滞剂成为主要的治疗方法。最近的证据表明，旨在切除肿瘤的早期手术干预可改善预后。本文的目的是报告3例卓-艾综合征患者的病史，并综述目前关于该综合征患者管理的文献。
