Price M
EMBL Heidelberg, Germany.
J Neurobiol. 1993 Oct;24(10):1385-99. doi: 10.1002/neu.480241010.
Members of the vertebrate Dlx- and Nkx2-homeobox-containing gene families exhibit closely related, complementary areas of gene expression in the developing forebrain. The expression domains and onset of gene transcription indicate that these genes may play a role in forebrain patterning, particularly in the diencephalon. In some cases, gene expression borders coincide with morphological boundaries separating functional and anatomical regions of the forebrain suggesting that the rostral region of the neural tube may indeed arise frm a segmented structure.
脊椎动物中含有Dlx和Nkx2同源框基因家族的成员，在发育中的前脑中表现出密切相关且互补的基因表达区域。基因表达结构域和基因转录的起始表明，这些基因可能在前脑模式形成中发挥作用，尤其是在间脑中。在某些情况下，基因表达边界与分隔前脑功能和解剖区域的形态边界重合，这表明神经管的头端区域可能确实起源于一种分段结构。
