Kubota T, Ishikura T, Jibiki I
Department of Neuropsychiatry, Kohritsu Mattoh Ishikawa Central Hospital, Mattoh, Japan.
Acta Neurol (Napoli). 1993 Jun;15(3):200-3.
One schizophrenic and two manic-depressive patients who after the administration of zotepine, a new antipsychotic and antimanic drug, developed alopecia areata, a kind of autoimmune disease, are reported. They recovered following the discontinuation or decrease in the dose of zotepine. These three cases of alopecia areata suggest that the antipsychotic drugs may induce autoimmune disease through their neuropsychological effect.
据报道,一名精神分裂症患者和两名躁郁症患者在服用新型抗精神病和抗躁狂药物佐替平后,患上了斑秃(一种自身免疫性疾病)。在停用佐替平或减少其剂量后,他们的病情得到了缓解。这三例斑秃病例表明,抗精神病药物可能通过其神经心理效应诱发自身免疫性疾病。