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蓝藻聚球藻属（Synechococcus sp.）菌株PCC 7942中谷氨酰胺合成酶基因（glnA）的表达在各种氮条件下均由单个类固氮启动子起始。

Expression of glnA in the cyanobacterium Synechococcus sp. strain PCC 7942 is initiated from a single nif-like promoter under various nitrogen conditions.

作者信息

Cohen-Kupiec R, Gurevitz M, Zilberstein A

机构信息

Department of Botany, Tel Aviv University, Ramat-Aviv, Israel.

出版信息

J Bacteriol. 1993 Dec;175(23):7727-31. doi: 10.1128/jb.175.23.7727-7731.1993.

DOI:10.1128/jb.175.23.7727-7731.1993
PMID:7902350
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC206936/
Abstract

The glnA mRNA, encoding glutamine synthetase, is differentially accumulated in the cyanobacterium Synechococcus sp. strain PCC 7942 in media containing different nitrogen sources. With the different nitrogen compounds, transcription of glnA initiated at a single site located -146 nucleotides upstream of the translation start site of the gene. A similarity of the nif-like promoter of the glnA gene of Anabaena sp. strain PCC 7120 and a binding-site sequence for the Synechococcus sp. strain PCC 7942 transcription regulator, NtcA, were found upstream of the transcription initiation site.

摘要

编码谷氨酰胺合成酶的glnA mRNA在含有不同氮源的蓝藻聚球藻属PCC 7942菌株中差异积累。对于不同的氮化合物，glnA的转录起始于位于该基因翻译起始位点上游146个核苷酸处的单个位点。在鱼腥藻属PCC 7120菌株glnA基因的nif样启动子与聚球藻属PCC 7942菌株转录调节因子NtcA的结合位点序列之间发现了相似性，该相似性位于转录起始位点上游。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/206936/2a78b723ce1f/jbacter00065-0233-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/206936/4275b9c8c21d/jbacter00065-0233-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/206936/2a78b723ce1f/jbacter00065-0233-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/206936/4275b9c8c21d/jbacter00065-0233-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/206936/2a78b723ce1f/jbacter00065-0233-b.jpg

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本文引用的文献

1
Anabaena sp. strain PCC 7120 bifA gene encoding a sequence-specific DNA-binding protein cloned by in vivo transcriptional interference selection.鱼腥藻属PCC 7120菌株的bifA基因，该基因编码一种通过体内转录干扰选择克隆的序列特异性DNA结合蛋白。
J Bacteriol. 1993 Jul;175(13):4025-35. doi: 10.1128/jb.175.13.4025-4035.1993.
2
Methylammonium transport in Anacystis nidulans R-2.集胞藻6803中甲基铵的转运
J Bacteriol. 1984 Oct;160(1):204-10. doi: 10.1128/jb.160.1.204-210.1984.
3
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
由大肠杆菌噬菌体HK022整合酶催化的鱼腥藻Anabaena sp.菌株PCC 7120中的位点特异性重组。
J Bacteriol. 2009 Jul;191(13):4458-64. doi: 10.1128/JB.00368-09. Epub 2009 May 8.
4
Ammonium assimilation in cyanobacteria.蓝细菌中的铵同化作用。
Photosynth Res. 2005;83(2):135-50. doi: 10.1007/s11120-004-2082-7.
5
A Synechococcus PglnA::luxAB fusion for estimation of nitrogen bioavailability to freshwater cyanobacteria.一种用于评估淡水蓝细菌氮生物可利用性的聚球藻PglnA::luxAB融合体。
Appl Environ Microbiol. 2003 Mar;69(3):1465-74. doi: 10.1128/AEM.69.3.1465-1474.2003.
6
Transcriptional activation of NtcA-dependent promoters of Synechococcus sp. PCC 7942 by 2-oxoglutarate in vitro.体外2-酮戊二酸对聚球藻属PCC 7942种NtcA依赖性启动子的转录激活作用
Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4251-5. doi: 10.1073/pnas.072587199. Epub 2002 Mar 26.
7
Nitrogen control in cyanobacteria.蓝细菌中的氮控制
J Bacteriol. 2001 Jan;183(2):411-25. doi: 10.1128/JB.183.2.411-425.2001.
8
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Appl Environ Microbiol. 1999 Aug;65(8):3651-9. doi: 10.1128/AEM.65.8.3651-3659.1999.
9
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J Bacteriol. 1999 May;181(9):2697-702. doi: 10.1128/JB.181.9.2697-2702.1999.
10
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J Bacteriol. 1998 Aug;180(16):4080-8. doi: 10.1128/JB.180.16.4080-4088.1998.
一种将DNA限制性内切酶片段放射性标记至高比活度的技术。
Anal Biochem. 1983 Jul 1;132(1):6-13. doi: 10.1016/0003-2697(83)90418-9.
4
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Nucleic Acids Res. 1984 Oct 25;12(20):7811-30. doi: 10.1093/nar/12.20.7811.
5
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Mol Gen Genet. 1983;192(1-2):187-97. doi: 10.1007/BF00327665.
6
Regulation of glutamine synthetase. I. Purification and properties of glutamine synthetase from Escherichia coli.谷氨酰胺合成酶的调控。I. 大肠杆菌谷氨酰胺合成酶的纯化及性质
Arch Biochem Biophys. 1966 Sep 26;116(1):177-92. doi: 10.1016/0003-9861(66)90026-9.
7
Genetic engineering of the cyanobacterial chromosome.蓝细菌染色体的基因工程
Methods Enzymol. 1987;153:215-31. doi: 10.1016/0076-6879(87)53055-5.
8
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EMBO J. 1986 Nov;5(11):2789-98. doi: 10.1002/j.1460-2075.1986.tb04569.x.
9
Probing the Escherichia coli glnALG upstream activation mechanism in vivo.
Proc Natl Acad Sci U S A. 1988 Dec;85(23):8934-8. doi: 10.1073/pnas.85.23.8934.
10
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J Bacteriol. 1988 Dec;170(12):5452-9. doi: 10.1128/jb.170.12.5452-5459.1988.