Olsson G, Held P
Cardiovascular Medicine, Astra Hässle AB, Mölndal, Sweden.
Am J Cardiol. 1993 Dec 16;72(19):156G-160G. doi: 10.1016/0002-9149(93)90122-s.
This article discusses therapy with beta blockade and thrombolytic agents in acute myocardial infarction. In large and well-controlled studies both treatment strategies have been shown to increase survival. Both therapies have also been demonstrated to be safe in acute myocardial infarction. Historically, the 2 different treatment strategies have been tested during different time periods, resulting in few studies with the main objective to study the combined effects of the 2 agents. From the data that are presently available, however, there is a clear suggestion of additive beneficial effect and the 2 treatments given in combination are well tolerated.
本文讨论了急性心肌梗死中β受体阻滞剂和溶栓药物的治疗。在大型且严格对照的研究中，这两种治疗策略均已显示可提高生存率。这两种疗法在急性心肌梗死中也已被证明是安全的。从历史上看，这两种不同的治疗策略是在不同时间段进行测试的，因此很少有以研究这两种药物联合效果为主要目的的研究。然而，根据目前可得的数据，有明确迹象表明存在相加的有益效果，且两种治疗联合使用耐受性良好。
