体外实验在动物福利中的作用。
The role of in vitro experiments in animal welfare.
作者信息
Rasmussen E S
机构信息
National Food Agency of Denmark, Søborg.
出版信息
Hum Exp Toxicol. 1993 Nov;12(6):522-7. doi: 10.1177/096032719301200610.
PMID:7904469
Abstract
The prospects of replacing animal experiments with other types of toxicological studies are considered, and the use of human data and in vitro experiments are discussed. Ongoing validation studies of in vitro methods for evaluation of acute toxicity, local irritation, target organ toxicity, tumour promotion and teratogenicity are presented.
摘要
文中探讨了用其他类型毒理学研究取代动物实验的前景，并讨论了人类数据和体外实验的应用。还介绍了目前针对急性毒性、局部刺激性、靶器官毒性、肿瘤促进作用和致畸性评估的体外方法的验证研究。
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