Wang B J, Lee J Y, Wang R C
Department of Dermatology, National Cheng-Kung University Hospital, Tainan, Taiwan, R.O.C.
J Formos Med Assoc. 1993 Aug;92(8):755-8.
Fiberglass is widely used for insulation and as a reinforcement filling material. Handling fiberglass products may induce contact dermatitis. We report on the first two cases of fiberglass dermatitis reported in Taiwan. The first patient suffered from a severe pruritic eruption two hours after repairing a roof with wave-form ceiling boards. Erythematous maculopapules were present on both hands and finger webs. The second patient was a quality controller of printed circuit boards (PRCBs). She presented with erythematous maculopapules on the face and excoriated papules and lichenified plaques on the trunk and forearms, which had been present for two years. Scrapings of the skin lesions from both patients showed fiberglass spicules of 7.5 to 8 microns in diameter. Similar fibers were detected in scrapings from the wave-form ceiling board and PRCB. Histopathology of the second case revealed spongiotic psoriasiform dermatitis. Patch tests in case 2 with the plastics and glues series, epoxy resin and scrapings from the PRCBs were all negative. Fiberglass dermatitis may be easily misdiagnosed. Clinically, it may resemble scabies, eczematous dermatitis, folliculitis, petechiae and urticaria. A high index of suspicion is essential for a correct diagnosis.
玻璃纤维被广泛用于绝缘以及作为增强填充材料。处理玻璃纤维制品可能会引发接触性皮炎。我们报告台湾首例两例玻璃纤维皮炎病例。首例患者在用波形天花板板修理屋顶两小时后，双手及指蹼出现严重瘙痒性皮疹，为红斑性丘疹。第二例患者是印刷电路板质量控制员，面部出现红斑性丘疹，躯干及前臂出现抓破的丘疹及苔藓化斑块，症状已持续两年。两名患者皮肤损害刮片均显示直径为7.5至8微米的玻璃纤维针状体。在波形天花板板及印刷电路板刮片中也检测到类似纤维。第二例组织病理学显示海绵状银屑病样皮炎。第二例患者对塑料和胶水系列、环氧树脂及印刷电路板刮片进行斑贴试验均为阴性。玻璃纤维皮炎可能容易被误诊。临床上，它可能类似疥疮、湿疹性皮炎、毛囊炎、瘀点及荨麻疹。高度怀疑对于正确诊断至关重要。
