Straub E
Res Exp Med (Berl). 1976 Aug 25;168(2):81-7. doi: 10.1007/BF01851897.
Eight pediatric patients presenting with acute renal failure (shock kidney, anuria continuing for three to five days) were treated with L-thyroxine (p.o. 5-6 mug per kg per day). Dialysis was not used. Diuresis started within 34 to 46 hours. Serum levels of urea and creatinine normalized within a very short time. The results are discussed on the basis of a new hypothesis concerning the RPF- and GFR-raising action of thyroid hormone in the normal situation and in acute renal failure.
八名患有急性肾衰竭(休克肾,无尿持续三至五天)的儿科患者接受了左旋甲状腺素治疗(口服,每天每千克体重5 - 6微克)。未使用透析。在34至46小时内开始利尿。尿素和肌酐的血清水平在很短时间内恢复正常。基于关于甲状腺激素在正常情况和急性肾衰竭中提高肾血浆流量(RPF)和肾小球滤过率(GFR)作用的新假说对结果进行了讨论。