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左旋甲状腺素在急性肾衰竭中的作用。

Effects of L-thyroxine in acute renal failure.

作者信息

Straub E

出版信息

Res Exp Med (Berl). 1976 Aug 25;168(2):81-7. doi: 10.1007/BF01851897.

DOI:10.1007/BF01851897
PMID:790499
Abstract

Eight pediatric patients presenting with acute renal failure (shock kidney, anuria continuing for three to five days) were treated with L-thyroxine (p.o. 5-6 mug per kg per day). Dialysis was not used. Diuresis started within 34 to 46 hours. Serum levels of urea and creatinine normalized within a very short time. The results are discussed on the basis of a new hypothesis concerning the RPF- and GFR-raising action of thyroid hormone in the normal situation and in acute renal failure.

摘要

八名患有急性肾衰竭(休克肾,无尿持续三至五天)的儿科患者接受了左旋甲状腺素治疗(口服,每天每千克体重5 - 6微克)。未使用透析。在34至46小时内开始利尿。尿素和肌酐的血清水平在很短时间内恢复正常。基于关于甲状腺激素在正常情况和急性肾衰竭中提高肾血浆流量(RPF)和肾小球滤过率(GFR)作用的新假说对结果进行了讨论。

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Effects of L-thyroxine in acute renal failure.左旋甲状腺素在急性肾衰竭中的作用。
Res Exp Med (Berl). 1976 Aug 25;168(2):81-7. doi: 10.1007/BF01851897.
2
[Thyroxine treatment in acute renal failure (author's transl)].急性肾衰竭的甲状腺素治疗(作者译)
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引用本文的文献

1
Nonthyroidal illness and the cardiorenal syndrome.非甲状腺疾病与心脏-肾脏综合征。
Nat Rev Nephrol. 2013 Oct;9(10):599-609. doi: 10.1038/nrneph.2013.170. Epub 2013 Sep 3.
2
Thyroid hormones for acute kidney injury.用于急性肾损伤的甲状腺激素。
Cochrane Database Syst Rev. 2013 Jan 31;2013(1):CD006740. doi: 10.1002/14651858.CD006740.pub2.
3
Effect of L-thyroxine on renal excretion of water and electrolytes in both normal and mercury-intoxicated rats.
Urol Res. 1980;8(3):189-96. doi: 10.1007/BF00256416.
4
New approaches to the treatment of acute renal failure.急性肾衰竭的新治疗方法。
Pediatr Nephrol. 1987 Jul;1(3):339-47. doi: 10.1007/BF00849233.
5
Management of acute renal failure in children.儿童急性肾衰竭的管理
Pediatr Nephrol. 1990 Jul;4(4):358. doi: 10.1007/BF00862518.