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[沙门菌病后风湿症]

[Post-salmonellosis rheumatism].

作者信息

Lemaire V, Ryckewaert A

出版信息

Rev Rhum Mal Osteoartic. 1976 Oct;43(10):561-3.

PMID:790532
Abstract

Reports of forty-six cases of aseptic polyarthritis following intestinal Salmonlla infections have been published. The organism involved is always a "minor" Salmonella either typhimurium or enteritidis. The interval separating the diarrhoea from the joint manifestations is usually one or two weeks. Post-salmonellosis rheumatism is most frequently polyarthritis involving the large joints accompanied by fever that is sometimes high. The sedimentation rate is increased and hyperleucytosis and discrete anaemia may also be present. Salmonella infection is established by the presence of the organism in the stools and a positive sero-diagnosis. In all cases the polyarthritis is cured by anti-inflammatory treatment in 1-6 months. HLA W27 antigen is present in the majority of the patients although spondylarthritis is not seen during the evolution. Although the number of cases of post-salmonellosis rheumatism is very small and the connection between the salmonellosis and the rheumatism has not been demonstrated, it is valuable, in cases of acute polyarthritis following enteritis, to carry out coproculture and serodiagnosis of salmonellosis.

摘要

已发表了46例肠道沙门氏菌感染后无菌性多关节炎的报告。所涉及的菌株总是“次要的”沙门氏菌,即鼠伤寒沙门氏菌或肠炎沙门氏菌。腹泻与关节表现之间的间隔通常为一或两周。沙门氏菌病后风湿症最常见的是累及大关节的多关节炎,并伴有有时高热的发热症状。血沉加快,也可能出现白细胞增多和轻度贫血。通过粪便中存在该菌株及血清学诊断阳性来确诊沙门氏菌感染。在所有病例中,多关节炎经抗炎治疗1至6个月后治愈。大多数患者存在HLA W27抗原,尽管在病程中未出现脊柱关节炎。虽然沙门氏菌病后风湿症的病例数非常少,且沙门氏菌病与风湿症之间的关联尚未得到证实,但在肠炎后急性多关节炎的病例中,进行沙门氏菌病的粪便培养和血清学诊断是有价值的。

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