Suga K, Nishigauchi K, Kume N, Uchisako H, Nakanishi T, Umemoto S, Fujii T, Fukuda S, Matsuzaki M
Department of Radiology, Yamaguchi University School of Medicine.
Kaku Igaku. 1993 Dec;30(12):1465-73.
We evaluated various radionuclide studies performed in the 8 patients with Takayasu's arteritis over the past six years. Radionuclide angiography was performed in 5 patients to investigate the lesions of the branches of the aortic arch, and it demonstrated abnormalities of the affected arteries in 4 patients. Pulmonary perfusion scan demonstrated single or multiple reduced perfusion sites in all the 5 patients examined, while chest radiographies of these patients did not show any abnormalities in the reduced perfusion sites except one case. Renal scintigraphy revealed reduced renal blood flow in 3 patients. In one of those patients, MRI, CT and DSA studies could not detect any stenotic change in the renal artery. Exercise thallium scan revealed myocardial ischemic changes in 2 patients. One of them had angina pectoris, but another patient did not have any complaints. Of the 6 patients who were examined more than one kind of radionuclide studies, five patients showed abnormalities in more than one study. Ambiguous symptoms at the initial stage and rareness of Takayasu's arteritis may delay diagnosis. Radionuclide studies, which can be performed easily and noninvasively to investigate various organs and to depict multiple vascular involvement, seem to be a useful diagnostic tool of this disease.
我们评估了过去六年中对8例大动脉炎患者进行的各种放射性核素检查。对5例患者进行了放射性核素血管造影以研究主动脉弓分支的病变，其中4例患者显示受累动脉异常。肺灌注扫描显示所有5例受检患者存在单个或多个灌注减低区，而这些患者的胸部X线片除1例外在灌注减低区未显示任何异常。肾闪烁显像显示3例患者肾血流减少。其中1例患者，MRI、CT和DSA检查未发现肾动脉有任何狭窄改变。运动铊扫描显示2例患者有心肌缺血改变。其中1例有胸痛，但另1例患者无任何不适主诉。在接受不止一种放射性核素检查的6例患者中，5例患者在不止一项检查中显示异常。大动脉炎初期症状不明确且发病率低可能会延迟诊断。放射性核素检查可以轻松、无创地对各种器官进行检查并描绘多处血管受累情况，似乎是该病一种有用的诊断工具。
