接受β受体阻滞剂治疗的患者在双嘧达莫负荷试验期间出现心搏停止和心动过缓。

Asystole and bradycardia during dipyridamole stress testing in patients receiving beta blockers.

作者信息

Roach P J, Magee M A, Freedman S B

机构信息

Department of Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales Australia.

出版信息

Int J Cardiol. 1993 Nov;42(1):92-4. doi: 10.1016/0167-5273(93)90108-s.

DOI:10.1016/0167-5273(93)90108-s

PMID:7906680

Abstract

Only rarely have serious side effects been reported with the use of intravenous dipyridamole. We describe two cases of severe bradycardia, of which one led to asystole, in patients undergoing dipyridamole-thallium studies. The association between beta blocker therapy and the seven reported cases of asystole with dipyridamole is discussed and mechanisms postulated. Some caution is advised when patients on beta blockers or similar medications have dipyridamole-thallium studies.

摘要

使用静脉注射双嘧达莫时，严重副作用的报告极为罕见。我们描述了两例在进行双嘧达莫-铊心肌显像检查的患者中出现严重心动过缓的病例，其中一例导致心脏停搏。文中讨论了β受体阻滞剂治疗与七例报告的双嘧达莫致心脏停搏病例之间的关联，并提出了相关机制。对于正在服用β受体阻滞剂或类似药物的患者进行双嘧达莫-铊心肌显像检查时，建议谨慎行事。