Hanabayashi T, Imai A, Itoh N, Tamaya T
Department of Obstetrics and Gynecology, Gifu University School of Medicine, Japan.
Int J Gynaecol Obstet. 1993 Dec;43(3):297-304. doi: 10.1016/0020-7292(93)90519-3.
Clinical diagnosis of cervical carcinoma fails to detect the location and extent of tumor invasion to cervical stroma and parametria. This study attempted to assess the accuracy of gadopentetate dimeglumine (Gd-DTPA)-enhanced magnetic resonance imaging (MRI) in the evaluation for the extent of cervical carcinoma.
A total of 41 patients with primary untreated cervical carcinoma underwent MRI throughout the staging evaluations before surgical treatment.
Without Gd-DPTA, T1-weighted images were less effective than T2-weighted images for MRI of pelvic organs. Gd-DTPA-enhanced T1-weighted images provided information similar to those of T2-weighted appearances, and distinguished the normal parametrium or vaginal wall from malignant invaded lesions more clearly.
The enhancement with Gd-DTPA may increase the ability of MRI to provide a positive spread/metastasis staging.
宫颈癌的临床诊断无法检测肿瘤浸润宫颈基质和宫旁组织的位置及范围。本研究旨在评估钆喷酸葡胺（Gd-DTPA）增强磁共振成像（MRI）在评估宫颈癌范围方面的准确性。
共有41例未经治疗的原发性宫颈癌患者在手术治疗前进行了全面分期评估的MRI检查。
未使用Gd-DPTA时，T1加权图像在盆腔器官MRI检查中不如T2加权图像有效。Gd-DTPA增强T1加权图像提供的信息与T2加权图像相似，并且能更清晰地将正常宫旁组织或阴道壁与恶性浸润病变区分开来。
Gd-DTPA增强可能会提高MRI进行阳性播散/转移分期的能力。
