Alhainen K, Riekkinen P J
Department of Neurology, University of Kuopio, Finland.
Acta Neurol Scand Suppl. 1993;149:16-21. doi: 10.1111/j.1600-0404.1993.tb04248.x.
We have studied whether it is possible to discriminate responders to tacrine treatment from patients nonresponsive to tacrine in Alzheimer's disease. The results indicate that mildly demented patients will most likely gain a benefit of tacrine treatment. Neuropsychological tests on attention and working memory after a single dose of tacrine might be useful as well as a single dose pharmaco-EEG in discriminating responders to treatment.
我们研究了在阿尔茨海默病中，是否有可能区分对他克林治疗有反应者和对他克林无反应者。结果表明，轻度痴呆患者最有可能从他克林治疗中获益。单次服用他克林后进行的注意力和工作记忆神经心理学测试以及单次服用他克林后的药物脑电图，在区分治疗反应者方面可能同样有用。
