Caligiuri M P
Department of Psychiatry, University of California, San Diego.
Mov Disord. 1994 Jan;9(1):57-63. doi: 10.1002/mds.870090109.
The need for objectivity in the assessment of parkinsonism prompted the development of a portable transducer capable of quantifying muscular rigidity. This paper describes the development and use of a device for measuring wrist rigidity and reports the preliminary findings from 25 normal healthy controls and 29 patients, many of whom were undergoing antiparkinsonian treatment to alleviate rigidity or antipsychotic treatment, which produced parkinsonian rigidity. An objective rigidity score, representing the degree to which motor activity increases muscular stiffness in the wrist, correlates highly with clinical ratings of parkinsonian rigidity and demonstrates 89% specificity and 82% sensitivity. Unlike previous techniques for quantifying rigidity, this transducer offers greater portability and apparent face validity.
在帕金森病评估中对客观性的需求促使了一种能够量化肌肉僵硬程度的便携式传感器的开发。本文描述了一种用于测量手腕僵硬程度的设备的开发和使用,并报告了来自25名正常健康对照者和29名患者的初步研究结果,其中许多患者正在接受抗帕金森病治疗以减轻僵硬程度,或接受抗精神病治疗,而后者会导致帕金森病性僵硬。一个客观的僵硬评分代表了运动活动增加手腕肌肉僵硬的程度,与帕金森病性僵硬的临床评分高度相关,特异性为89%,敏感性为82%。与以前量化僵硬程度的技术不同,这种传感器具有更高的便携性和表面效度。