Cuello A C
Lancet. 1978 Aug 5;2(8084):291-3. doi: 10.1016/s0140-6736(78)91692-6.
Immunoreactive leucine-encephalin has been found in nerve terminals and cell bodies of neurons in the human brain. The most intense reaction was found in the globus pallidus, followed by the spinal nucleus of the trigeminal nerve. These observations suggest that in man endogenous opioid substances may play an important part in neurotransmission in areas of the central nervous system related to pain and locomotor activity.
在人脑神经元的神经末梢和细胞体中已发现免疫反应性亮氨酸脑啡肽。在苍白球中发现反应最为强烈,其次是三叉神经脊束核。这些观察结果表明,在人类中,内源性阿片样物质可能在与疼痛和运动活动相关的中枢神经系统区域的神经传递中起重要作用。