牛富含组氨酸糖蛋白是牛血浆因子XIIIa的一种底物。

Bovine histidine-rich glycoprotein is a substrate for bovine plasma factor XIIIa.

作者信息

Halkier T, Andersen H, Vestergaard A, Magnusson S

机构信息

Department of Molecular Biology and Plant Physiology, University of Aarhus, Denmark.

出版信息

Biochem Biophys Res Commun. 1994 Apr 15;200(1):78-82. doi: 10.1006/bbrc.1994.1416.

DOI:10.1006/bbrc.1994.1416

PMID:7909439

Abstract

Histidine-rich glycoprotein was purified from bovine plasma and the identity of the protein confirmed through amino acid sequencing. Activated bovine factor XIIIa catalyzed the incorporation of 1 nmol of 1,4-[14C]putrescine into 1 nmol of bovine histidine-rich glycoprotein, showing that histidine-rich glycoprotein has the ability to participate in transglutaminase-catalyzed reactions in vivo.

摘要

从牛血浆中纯化出富含组氨酸的糖蛋白，并通过氨基酸测序确认了该蛋白的身份。活化的牛因子XIIIa催化1 nmol的1,4-[14C]腐胺掺入1 nmol的牛富含组氨酸的糖蛋白中，表明富含组氨酸的糖蛋白具有在体内参与转谷氨酰胺酶催化反应的能力。