Kawasaki S, Makuuchi M, Miyagawa S, Kakazu T
First Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
J Am Coll Surg. 1994 May;178(5):480-6.
The clinical outcomes of patients with carcinoma of the proximal bile duct who underwent portal embolization of the right lobe followed by right extended lobectomy with (n = 3) and without (n = 9) pancreatoduodenectomy, are described. Preoperative embolization of the portal venous branch of the right hepatic lobe, which was performed with the intent of preventing postoperative hepatic failure, induced a significant increase in the volume of the future remnant liver (left lobe) (from 437 +/- 88 to 544 +/- 97 milliliters, p < 0.01). No patients died in the hospital after the resectional operation. One patient, who had poorly differentiated adenocarcinoma, died as a result of tumor recurrence 12 months after operation, and in another patient, distant lymph node metastases were found. The remaining ten patients are alive and well with no signs of recurrence. The three who underwent hepatopancreatoduodenectomy are leading a normal life 14, 21 and 22 months postoperatively.
本文描述了近端胆管癌患者接受右叶门静脉栓塞后，分别进行（n = 3）和未进行（n = 9）胰十二指肠切除术的右肝扩大切除术的临床结果。为预防术后肝衰竭而进行的右肝叶门静脉分支术前栓塞，使未来残余肝（左叶）体积显著增加（从437±88毫升增至544±97毫升，p<0.01）。切除术后无患者在医院死亡。1例低分化腺癌患者术后12个月因肿瘤复发死亡，另1例发现远处淋巴结转移。其余10例患者存活且状况良好，无复发迹象。接受肝胰十二指肠切除术的3例患者术后14、21和22个月生活正常。
