口服降糖药的临床应用。
Clinical use of oral hypoglycemic agents.
作者信息
Hagg S A
出版信息
Am J Hosp Pharm. 1976 Sep;33(9):943-7.
PMID:790951
Abstract
The pharmacology, mechanism of action, indications, interactions and clinical effectiveness of oral hypoglycemic agents, specifically the sulfonylureas and biguanides, are reviewed. The use of these agents is discussed in view of the findings of the University Group Diabetes Program study. It is concluded that oral hypoglycemic agents, in conjunction with diet and weight reduction, may be useful in selected patients but that insulin is preferable in most instances.
摘要
本文综述了口服降糖药，特别是磺脲类和双胍类药物的药理学、作用机制、适应证、相互作用及临床疗效。结合大学组糖尿病项目研究的结果对这些药物的使用进行了讨论。得出的结论是，口服降糖药与饮食控制及减轻体重相结合，可能对部分患者有用，但在大多数情况下胰岛素治疗更为可取。
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