Baumel B
Baumel-Eisner Neuromedical Institute, Miami Beach, FL 33154-2025.
Neurology. 1994 May;44(5 Suppl 3):S13-7.
The management of migraine usually centers on two approaches: preventive and abortive therapy. Preventive therapy, designed to reduce the frequency, duration, and intensity of attacks, can be accomplished through a wide variety of medications. The most commonly used are beta-blockers, but calcium channel blockers, antidepressants, anticonvulsants, and nonsteroidal anti-inflammatory agents have all been used with success. Agents used in abortive migraine therapy treat the intensity and duration of pain, as well as the associated symptoms. New treatment options have been developed, including such newly approved medications as sumatriptan. Sumatriptan is a very effective agent that has joined the ranks of other effective abortive migraine treatments, such as ergotamine, dihydroergotamine, and nonsteroidal anti-inflammatory agents, as well as narcotic analgesics. New delivery systems, such as the nasal-spray formulation of butorphanol, allow for a route of administration previously unavailable to migraine sufferers. These new and developing treatment modalities will give physicians a wider choice of outpatient therapy options.
预防性治疗和发作期治疗。预防性治疗旨在减少发作的频率、持续时间和强度，可通过多种药物来实现。最常用的是β受体阻滞剂，但钙通道阻滞剂、抗抑郁药、抗惊厥药和非甾体抗炎药也都已成功应用。用于偏头痛发作期治疗的药物可缓解疼痛的强度和持续时间以及相关症状。已经开发出了新的治疗选择，包括新批准的药物如舒马曲坦。舒马曲坦是一种非常有效的药物，已加入其他有效的偏头痛发作期治疗药物行列，如麦角胺、二氢麦角胺、非甾体抗炎药以及麻醉性镇痛药。新的给药系统，如布托啡诺鼻喷雾剂，为偏头痛患者提供了一种以前无法获得的给药途径。这些新的和正在发展的治疗方式将为医生提供更广泛的门诊治疗选择。
