[卡拉泽丁的药理特性]
[The pharmacological properties of karazedin].
作者信息
Barkov N K, Serpilina N M, Surkova L A, Sharkova L M, Rusakov D Iu, Tiurina I V
出版信息
Eksp Klin Farmakol. 1994 Mar-Apr;57(2):4-6.
PMID:7911367
Abstract
The original agent 1,2,3,4,5,5a,6,10b-octahydroazepino-[4,5-b]indole (carazedine), an analog of the highly active antipsychotic drug carbidine, was synthesized. This agent was found to have various psychotropic activities and to be superior to carbidine, as shown by a number of tests, and combine properties typical of neuroleptics and tranquilizers. The toxicity of carazedine and carbidine was equal.
摘要
最初的药剂1,2,3,4,5,5a,6,10b - 八氢氮杂环庚三烯并-[4,5 - b]吲哚（卡雷嗪），一种高活性抗精神病药物卡比定的类似物，被合成出来。通过多项测试表明，这种药剂具有多种精神活性，且优于卡比定，并兼具典型的抗精神病药物和镇静剂的特性。卡雷嗪和卡比定的毒性相当。
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