Van Hest B J, Molloy P L, Frankham R, Sheldon B L
CSIRO Division of Animal Production, North Ryde, NSW, Australia.
Anim Genet. 1994 Apr;25(2):109-11.
In work aimed at extending the chicken genome linkage map, a heat shock protein gene, HSP108, was shown by restriction fragment length polymorphism (RFLP) analysis to be linked to one of two replication histone gene clusters located on chromosome 1. Linkage was estimated using the LOD score method, on segregation data from seven pedigreed three-generation families (245 individuals). The maximum likelihood estimate of the recombination fraction (theta) was 0.215.
在旨在扩展鸡基因组连锁图谱的研究工作中，通过限制性片段长度多态性（RFLP）分析表明，一个热休克蛋白基因HSP108与位于1号染色体上的两个复制组蛋白基因簇之一相连。利用LOD分数法，根据来自7个三代家系（共245个个体）的分离数据估算连锁情况。重组率（θ）的最大似然估计值为0.215。
