Carroll S B, Gates J, Keys D N, Paddock S W, Panganiban G E, Selegue J E, Williams J A
Howard Hughes Medical Institute, Madison, WI.
Science. 1994 Jul 1;265(5168):109-14. doi: 10.1126/science.7912449.
Butterfly wings display pattern elements of many types and colors. To identify the molecular processes underlying the generation of these patterns, several butterfly cognates of Drosophila appendage patterning genes have been cloned and their expression patterns have been analyzed. Butterfly wing patterns are organized by two spatial coordinate systems. One system specifies positional information with respect to the entire wing field and is conserved between fruit flies and butterflies. A second system, superimposed on the general system and involving several of the same genes, operates within each wing subdivision to elaborate discrete pattern elements. Eyespots, which form from discrete developmental organizers, are marked by Distal-less gene expression. These circular pattern elements appear to be generated by a process similar to, and perhaps evolved from, proximodistal pattern formation in insect appendages.
蝴蝶翅膀呈现出多种类型和颜色的图案元素。为了确定这些图案形成背后的分子过程，已克隆了果蝇附肢图案形成基因的几个蝴蝶同源基因，并分析了它们的表达模式。蝴蝶翅膀图案由两个空间坐标系组织而成。一个系统指定相对于整个翅膀区域的位置信息，并且在果蝇和蝴蝶之间是保守的。第二个系统叠加在一般系统之上，涉及几个相同的基因，在每个翅膀细分区域内运作以细化离散的图案元素。由离散的发育组织者形成的眼斑，由Distal-less基因表达标记。这些圆形图案元素似乎是由一个类似于昆虫附肢近端到远端图案形成的过程产生的，并且可能是从该过程进化而来的。
