Alvarez C, Robert M, Sherman S, Reber H A
Department of Surgery, University of California-Los Angeles School of Medicine.
Arch Surg. 1994 Jul;129(7):765-8. doi: 10.1001/archsurg.1994.01420310097018.
The placement of stents has been proposed as a possible modality to treat pancreatic diseases. Ductal changes observed on endoscopic retrograde cholangiopancreatography during stenting are believed to be reversible when the stents are removed. We describe a patient with normal anatomy on baseline pancreatograms who underwent endoscopic sphincterotomy, followed by stent placement for 9 months. Symptoms progressed, leading to a pancreaticoduodenectomy. Histologic evaluation of the head of the pancreas revealed more extensive inflammatory changes in the duct and parenchyma drained by the stent. This suggests that stent-induced changes noted on pancreatography correspond to parenchymal changes that may be severe and irreversible.
支架置入已被提议作为治疗胰腺疾病的一种可能方式。支架置入过程中在内镜逆行胰胆管造影术上观察到的导管变化被认为在移除支架后是可逆的。我们描述了一名患者，其基线胰胆管造影显示解剖结构正常，该患者接受了内镜括约肌切开术，随后置入支架9个月。症状进展，最终进行了胰十二指肠切除术。胰腺头部的组织学评估显示，支架引流的导管和实质中有更广泛的炎症变化。这表明在胰胆管造影上观察到的支架诱导变化对应于可能严重且不可逆的实质变化。
