Multiple endocrine neoplasia type 1. Clinical features and screening.

The clinical and biochemical features of multiple endocrine neoplasia type 1 are presented with a focus on methods for the early detection of the parathyroid, pituitary, and endocrine pancreas. A rationale is provided for early detection of MEN 1-associated abnormalities including a discussion of improved quality of life and reduction of morbidity and mortality.