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俄罗斯人群中载脂蛋白B基因多态性

Apolipoprotein B gene polymorphism in a Russian population.

作者信息

Stepanov V A, Puzyrev V P

机构信息

Molecular Genetics Laboratory, Russian Academy of Medical Sciences, Tomsk.

出版信息

Hum Biol. 1994 Jun;66(3):527-31.

PMID:7913079
Abstract

The XbaI and EcoRI restriction fragment length polymorphisms at the apolipoprotein B gene locus were studied using the polymerase chain reaction. The allele, genotype, and haplotype frequencies in Russians from west Siberia were determined. Linkage disequilibrium between the XbaI and EcoRI loci was detected.

摘要

利用聚合酶链反应研究了载脂蛋白B基因位点的XbaI和EcoRI限制性片段长度多态性。测定了西西伯利亚俄罗斯人的等位基因、基因型和单倍型频率。检测到XbaI和EcoRI位点之间的连锁不平衡。

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