De Bray J M, Missoum A, Dubas F, Joseph P A, Lhoste P, Emile J, Saumet J L
Explorations Fonctionnelles Vasculaires, CHU d'Angers.
J Mal Vasc. 1994;19(1):35-40.
The aim of this prospective study was to investigate the additional information provided by transcranial pulsed Doppler for the determination of the upper part of dissections of the carotid and vertebral arteries and following-up. Earlier results concerning the role of ultrasound investigations for this indication have been presented elsewhere. Twenty-nine patients were examined (17 females, 12 males; mean age 43 years). All had arterial dissections confirmed by arteriography. There were 24 carotid dissections and 12 vertebral dissections. Investigations were performed during the acute phase and 2 months later. Most of the severe endocranial stenoses were identified by transcranial Doppler: 5 out of 6 severe stenoses of the carotid siphon and 6 out of 7 vertebral stenoses. The haemodynamic effect as measured by sylvian flow was significantly greater (p < 0.01) after a permanent ischaemic event than after temporary events and improved significantly with time (p < 0.008). There was no significant variation in the pulsatility transmission index (PTI), but this index requires a reference artery and is not particularly adapted in cases with bilateral dissection. Collateral perfusion, observed during the acute phase in all cases of occlusion and in 6 of the 8 carotid stenosis, was insufficient in half of the cases. Transcranial pulsed Doppler can be used to guide arteriography and helps determine the length of the dissection. It provides an easy way to assess the haemodynamic consequences of the dissection and is quite useful during follow-up.
这项前瞻性研究的目的是探讨经颅脉冲多普勒在确定颈动脉和椎动脉夹层上部及随访方面所提供的额外信息。关于超声检查在此适应症中的作用的早期结果已在其他地方发表。对29例患者进行了检查(17例女性,12例男性;平均年龄43岁)。所有患者均经动脉造影证实有动脉夹层。其中有24例颈动脉夹层和12例椎动脉夹层。在急性期和2个月后进行了检查。大多数严重的颅内狭窄通过经颅多普勒得以识别:颈内动脉虹吸部6例严重狭窄中的5例以及椎动脉狭窄7例中的6例。永久性缺血事件后通过大脑中动脉血流测量的血流动力学效应显著大于暂时性事件后(p < 0.01),且随时间显著改善(p < 0.008)。搏动传递指数(PTI)没有显著变化,但该指数需要一条参考动脉,并且在双侧夹层的情况下不太适用。在所有闭塞病例以及8例颈动脉狭窄中的6例急性期观察到的侧支灌注,有一半病例不足。经颅脉冲多普勒可用于指导动脉造影,并有助于确定夹层的长度。它提供了一种评估夹层血流动力学后果的简便方法,并且在随访期间非常有用。