柳氮磺胺吡啶治疗后HIV-赖特尔综合征患者CD4淋巴细胞计数的改善
Improvement in CD4 lymphocyte count in HIV-Reiter's syndrome after treatment with sulfasalazine.
作者信息
Disla E, Rhim H R, Reddy A, Taranta A
机构信息
Department of Medicine, Cabrini Medical Center, New York, NY 10003.
出版信息
J Rheumatol. 1994 Apr;21(4):662-4.
OBJECTIVE
To describe an observed improvement in CD4 lymphocytes in patients with Reiter's syndrome (RS) and human immunodeficiency virus (HIV) infection, after treatment with sulfasalazine (SFSZ). METHODS . Care series. We analyzed CD4 lymphocyte counts in 4 consecutive patients with RS and HIV disease before and after treatment with SFSZ.
RESULTS
CD4+ lymphocyte counts increased from a mean of 315 +/- 179 before treatment to 542 +/- 231 x 10(6)/l on followup (p < 0.03), in the absence of antiretroviral therapy. The significance of these observations is discussed.
CONCLUSION
Treatment of RS with SFSZ in HIV disease appears to be associated with an improvement in CD4 count.
目的
描述在柳氮磺胺吡啶（SFSZ）治疗后，赖特综合征（RS）合并人类免疫缺陷病毒（HIV）感染患者CD4淋巴细胞计数出现的改善情况。方法：病例系列研究。我们分析了4例连续的RS合并HIV疾病患者在SFSZ治疗前后的CD4淋巴细胞计数。
结果
在未进行抗逆转录病毒治疗的情况下，CD4 +淋巴细胞计数从治疗前的平均315±179增加到随访时的542±231×10⁶ /L（p <0.03）。讨论了这些观察结果的意义。
结论
在HIV疾病中，用SFSZ治疗RS似乎与CD4计数的改善有关。
Zotero 插件