Neurological examination abnormalities in neuroleptic-naive patients with first-break schizophrenia: preliminary results.

The authors report preliminary findings from an ongoing prospective study of neuroleptic-naive patients with first-break schizophrenia. They evaluated 17 of these patients and 15 normal subjects with a structured neurological examination before the patients received any medical treatment. The patients with schizophrenia showed significantly greater neurological impairment than did the normal comparison subjects.