Mori A, Takahashi T, Miyashita Y, Kasai H
Department of Physiology, Faculty of Medicine, University of Tokyo, Japan.
Neurosci Lett. 1994 Mar 14;169(1-2):199-202. doi: 10.1016/0304-3940(94)90391-3.
We investigated the quantal properties of the small glutamatergic EPSPs (S-type EPSPs) in the striatal medium spiny neurons using the whole-cell recording method. Amplitudes of unitary glutamatergic EPSCs displayed a single peak at about 4.7 pA that was unaffected by decreasing external Ca2+. This indicates that afferent fibers contact the medium spiny neuron with only a few, possibly one, release sites which generate no more than one quantum of EPSCs at a time.