Cesani F, Ernst R, Walser E, Villanueva-Meyer J
Department of Radiology, University of Texas Medical Branch, Galveston 77555.
Clin Nucl Med. 1994 Jun;19(6):532-4. doi: 10.1097/00003072-199406000-00014.
Technetium-99m sestamibi is known to localize in primary malignant and metastatic tumors. Specifically, brain, breast, thyroid, parathyroid, lung, and kidney tumors have been imaged. The Verner Morrison syndrome, which is caused by excessive vasoactive intestinal peptide (VIP), consists of watery diarrhea, hypokalemia, and achlorhydria. This condition is rarely associated with multiple endocrine neoplasia. The authors present a case of multiple endocrine neoplasia type I with visualization of a pancreatic VIPoma and parathyroid adenoma with Tc-99m MIBI.
已知锝-99m 甲氧基异丁基异腈可在原发性恶性肿瘤和转移性肿瘤中聚集。具体而言,已对脑、乳腺、甲状腺、甲状旁腺、肺和肾肿瘤进行了成像。由过量血管活性肠肽(VIP)引起的韦尔纳·莫里森综合征包括水样腹泻、低钾血症和无胃酸。这种情况很少与多发性内分泌肿瘤相关。作者报告了一例 I 型多发性内分泌肿瘤病例,通过锝-99m 甲氧基异丁基异腈显像发现了胰腺 VIP 瘤和甲状旁腺腺瘤。