Gupta M, Mazumder U K, Das S
Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India.
Indian J Exp Biol. 1994 Mar;32(3):216-7.
Hypotensive effect of the extract of leaves of C. colebrookianum was investigated. An extremely bitter fraction was isolated, which gave positive test for alkaloids. The fraction produced fall of blood pressure in a dose dependent manner. The fall of blood pressure was blocked by atropine. Hypertensive effects of adrenaline and noradrenaline were slightly antagonised by the alkaloidal extract.
对柯氏栝楼叶片提取物的降压作用进行了研究。分离出一种极苦的馏分，该馏分生物碱检测呈阳性。该馏分能使血压呈剂量依赖性下降。血压下降被阿托品阻断。生物碱提取物对肾上腺素和去甲肾上腺素的升压作用有轻微拮抗作用。
