Elami A, Merin G, Shushan Y
Department of Cardiothoracic Surgery, Shaare-Zedek Medical Center, Jerusalem, Israel.
Cardiovasc Surg. 1993 Jun;1(3):276-9.
The effect of using the internal mammary artery (IMA) as a conduit for revascularization on the outcome of early (< 30 days) coronary artery bypass graft surgery after acute myocardial infarction was determined. Forty patients were studied: 27 underwent urgent operation for ongoing ischaemia and/or haemodynamic instability early after acute myocardial infarction and 13 had emergency surgery for failed percutaneous transluminal coronary angioplasty associated with clinical and enzymatic evidence of myocardial infarction. Nine patients experienced low cardiac output before operation, in six of whom intra-aortic balloon counterpulsation was used to treat cardiogenic shock. In 26 patients (group 1) the left IMA was utilized with or without additional vein grafts. In the remainder (group 2, n = 14), only vein grafts were used. Group 1 patients were younger than those in group 2 (mean(s.d.) age 55(9) versus 67(8) years, P = 0.0001). Other preoperative and perioperative variables were similar in the two groups. There was one death in hospital (2%, group 2). Eight (31%) group 1 patients sustained postoperative low cardiac output compared with ten (71%) in group 2 (P < 0.04). Preoperative low cardiac output (P < 0.025) and non-use of the IMA (P < 0.05) were identified by univariate and multivariate analysis as the most significant independent predictors of low cardiac output after operation. Although age was excluded as a predictor of low cardiac output, it is concluded that the IMA is an adequate conduit that can safely be used in patients younger than 70 years of age undergoing myocardial revascularization during or early after acute myocardial infarction.
研究了使用乳内动脉(IMA)作为血管重建的管道对急性心肌梗死后早期(<30天)冠状动脉旁路移植手术结果的影响。共研究了40例患者:27例在急性心肌梗死后早期因持续缺血和/或血流动力学不稳定接受了急诊手术,13例因经皮腔内冠状动脉成形术失败并伴有心肌梗死的临床和酶学证据而接受了急诊手术。9例患者术前出现低心排血量,其中6例使用主动脉内球囊反搏治疗心源性休克。26例患者(第1组)使用了左IMA,可单独使用或联合其他静脉移植物。其余患者(第2组,n = 14)仅使用静脉移植物。第1组患者比第2组患者年轻(平均(标准差)年龄55(9)岁对67(8)岁,P = 0.0001)。两组的其他术前和围手术期变量相似。住院期间有1例死亡(2%,第2组)。第1组有8例(31%)患者术后出现低心排血量,而第2组为10例(71%)(P < 0.04)。单因素和多因素分析均显示,术前低心排血量(P < 0.025)和未使用IMA(P < 0.05)是术后低心排血量最显著的独立预测因素。虽然年龄被排除在低心排血量的预测因素之外,但得出的结论是,IMA是一种合适且安全的管道,可用于70岁以下在急性心肌梗死期间或之后早期接受心肌血管重建的患者。