实验性难治性休克中的心力衰竭
Heart failure in experimental refractory shock.
作者信息
Ledingham I M
出版信息
Eur J Intensive Care Med. 1976 Nov;2(3):111-7. doi: 10.1007/BF00579691.
PMID:791649
Abstract
Severe haemorrhagic shock was studied in a series of animal experiments. Reduction in myocardial oxygen and substrate utilisation in association with cardiac failure was demonstrated when the duration of shock was prolonged. The probable aetiological factors included ischaemia and the presence in the blood of certain vasoactive and metabolic depressant substances. It was concluded that the process leading to irreversible shock was multi-factorial in origin but failure appeared to play an important role.
摘要
在一系列动物实验中对严重失血性休克进行了研究。当休克持续时间延长时，证实了与心力衰竭相关的心肌氧和底物利用减少。可能的病因包括缺血以及血液中某些血管活性和代谢抑制物质的存在。得出的结论是，导致不可逆休克的过程在起源上是多因素的，但衰竭似乎起了重要作用。
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