Maes B, Fryns J P, Van Walleghem M, Van den Berghe H
Centre for Human Genetics, University of Leuven, Belgium.
Genet Couns. 1994;5(2):129-39.
In a large study of the psychosocial functioning of mentally retarded adults with fra(X) syndrome we also evaluated their personal independence. 58 mentally retarded adult men with a cytogenetically confirmed diagnosis of fra(X) syndrome and 58 fra(X) negative control persons with a comparable age, level of cognitive development, actual living conditions and length of institutionalization were evaluated with three Dutch standardized behavioral scales. In spite of comparable social competency scores in both research groups, two significant different aspects were found: 1) Fra(X) men obtained a higher level of elementary knowledge and skillfulness in rudimentary dealing with personal needs and household tasks in daily life in comparison with the control group; 2) moderately mentally retarded fra(X) adults were practising more preacademic reading, calculating and writing skills in daily life than control persons.
在一项针对患有脆性X综合征的成年智障者心理社会功能的大型研究中,我们还评估了他们的个人独立性。我们使用三个荷兰标准化行为量表,对58名经细胞遗传学确诊患有脆性X综合征的成年智障男性以及58名年龄、认知发展水平、实际生活状况和机构收容时长相当的脆性X阴性对照者进行了评估。尽管两个研究组的社会能力得分相当,但仍发现了两个显著不同的方面:1)与对照组相比,脆性X男性在日常生活中处理个人需求和家务任务的基本知识和技能水平更高;2)中度智障的脆性X成年人在日常生活中比对照者更多地练习学前阅读、计算和写作技能。