Skołyszewski J, Reinfuss M, Weiss M
Department of Radiation Oncology, Centre of Oncology-Maria Skłodowska-Curie Memorial Institute, Kraków, Poland.
Acta Oncol. 1994;33(5):561-5. doi: 10.3109/02841869409083936.
Between 1970 and 1985, 500 patients with urinary bladder carcinoma received external beam radiotherapy with curative intent at the Centre of Oncology in Kraków. The 5-year survival without evidence of cancer for T1 patients was 100% (5/5), for T2 48.7% (19/39), for T3 32% (128/400), and for T4 7.1% (4/56). In our patients the clinical T category was the only pretherapeutic prognostic parameter of statistical significance confirmed in uni- and multivariate analysis. The tolerance of therapy was poorer in patients who had partial transurethral resection of the bladder tumour performed prior to radiation therapy, and in those whose bladder volume was less than 200 ml. The additional irradiation of regional (pelvic) lymph nodes seemed to improve survival of patients with T3 bladder carcinoma.
1970年至1985年间，500例膀胱癌患者在克拉科夫肿瘤中心接受了旨在治愈的外照射放疗。T1期患者无癌证据的5年生存率为100%（5/5），T2期为48.7%（19/39），T3期为32%（128/400），T4期为7.1%（4/56）。在我们的患者中，临床T分期是单因素和多因素分析中唯一具有统计学意义的治疗前预后参数。在放疗前接受过膀胱肿瘤部分经尿道切除术的患者以及膀胱容量小于200 ml的患者中，治疗耐受性较差。对区域（盆腔）淋巴结进行额外照射似乎可提高T3期膀胱癌患者的生存率。
